PHA.06121.01 - K-InBT: Systems- and Synthetic Biology (Complete module description)

PHA.06121.01	5 CP
Module label	K-InBT: Systems- and Synthetic Biology
Module code	PHA.06121.01
Semester of first implementation
Faculty/Institute	Institut für Pharmazie
Module used in courses of study / semesters	Pharmaceutical and Industrial Biotechnology (MA120 LP) (Master) > Pharmazie PharmacIndusBiotech.MA120, Version of accreditation valid from WS 2019/20 > Spezialisierung Industrial Biotechnology Pharmaceutical and Industrial Biotechnology (MA120 LP) (Master) > Pharmazie PharmacIndusBiotech.MA120, Version of accreditation (WS 2015/16 - SoSe 2023) > Spezialisierung Industrial Biotechnology
Responsible person for this module
Further responsible persons	A. Tissier
Prerequisites	Modules of the first semester (A-Both, B-PhBT, C-Both, D-Both)
Skills to be acquired in this module	Knowledge of latest methods and approaches in molecular/modular cloning Overview of the various domains of synthetic biology Introduction to modeling of biological systems and networks Practical experience in modular cloning methods Practical experience in metabolic modeling
Module contents	Course K-InBT.1: Synthetic Biology Synthetic biology introduction: one word, many aspects %u2013 from modular cloning to genome assembly Molecular biology techniques: Gibson assembly and recombination based systems, re-striction enzyme based cloning systems (Golden Gate). Concept of standard parts and modular cloning systems Regulatory circuits and switches Course K-InBT.2: Systems Biology Modeling of biological networks (linear systems, dynamic systems; metabolic networks, regulatory networks) Simulation of models of biological networks and analysis of results (steady states and their stability, non-linear dynamics) Course K-InBT.3: Project seminar Introduction to Golden Gate cloning and modular assembly Application for metabolic engineering in yeast and/or Nicotiana benthamiana Stoichiometric modeling with CellNetAnalyzer Kinetic modeling with Copasi
Forms of instruction	Seminar (5 SWS) Course
Languages of instruction	German, English
Duration (semesters)	1 Semester Semester
Module frequency	jedes Wintersemester
Module capacity	unrestricted
Time of examination
Credit points	5 CP
Share on module final degree	Course 1: %; Course 2: %.
Share of module grade on the course of study's final grade	1

Module course label	Course type	Course title	SWS	Workload of independent learning	Sum workload
Course 1	Seminar	Project seminar	5		0
Course 2	Course	Selbststudium			0
Workload by module				150	150
Total module workload					150

Examination	Exam prerequisites	Type of examination
Course 1
Course 2
Final exam of module	Attestation on project seminar contents, Protocol, Oral presentation on a current research topic	Klausur
Exam repetition information

Prerequisites and conditions	Prerequisites	Frequency	Compulsory attendance	Share on module grade in percent
Course 1		Winter semester	No	%
Course 2		Winter semester	No	%