MLU
PHA.03535.02 - Optimization of bioprocesses (Complete module description)
Original version English
PHA.03535.02 5 CP
Module label Optimization of bioprocesses
Module code PHA.03535.02
Semester of first implementation
Faculty/Institute Institut für Pharmazie
Module used in courses of study / semesters
  • Pharmaceutical Biotechnology (MA120 LP) (Master) > Pharmazie Pharmaceut.Biotech.MA120, Version of accreditation (WS 2008/09 - WS 2015/16) > Pflichtmodule
Responsible person for this module
Further responsible persons
Dr. N. Volk
Prerequisites
Modul D: Introduction to Bioprocess Technology (Upstream Processing)
Skills to be acquired in this module
• Knowledge of mathematical modeling to optimization of bioprocesses • Foundations in the use of simulations languages • Using tools to identification, simulation and optimization • Application of models to optimization of bioprocesses • Knowledge of planning and preparation of bioreactor cultivations • Laboratory scale development of strategies for optimal bioprocessing technologies • Experience in the use of bioprocess cultivation techniques • Practical experience in the preparation and implementation of fermentations • Analyze and validate of results of fermentations
Module contents
Course E.1: Modeling and simulation • Principles of bioprocess modeling and optimization • Modeling concepts for biological systems and bioreactors • Dynamic modeling of bioreactors • Introduction in simulation language (MATLAB, Copasi, Celldesigner) • Case studies to simulation • Optimization of bioprocesses • Case studies to optimization
Course E.2: Control of bioreactor cultivations • Planning of a bioreactor cultivation process • Mathematical simulation of the process • Preparation of the bioprocess techniques and analytics • Experimental realization of the cultivation process • Analyze and validate the results • Identification of a model from the results • Describe and analyze the process
Forms of instruction Practical training (2 SWS)
Lecture (1 SWS)
Seminar (1 SWS)
Seminar (1 SWS)
Course
Languages of instruction German, English
Duration (semesters) 1 Semester Semester
Module frequency jedes Sommersemester
Module capacity unlimited
Time of examination
Credit points 5 CP
Share on module final degree Course 1: %; Course 2: %; Course 3: %; Course 4: %; Course 5: %.
Share of module grade on the course of study's final grade 1
Module course label Course type Course title SWS Workload of compulsory attendance Workload of preparation / homework etc Workload of independent learning Workload (examination and preparation) Sum workload
Course 1 Practical training Control of bioreactor cultivations 2 0
Course 2 Lecture Modeling and Simulation 1 0
Course 3 Seminar Modeling and Simulation 1 0
Course 4 Seminar Control of bioreactor cultivations 1 0
Course 5 Course Selbststudium 0
Workload by module 150 150
Total module workload 150
Examination Exam prerequisites Type of examination
Course 1
Course 2
Course 3
Course 4
Course 5
Final exam of module
1 attestation, 1 protocol, 5 exercises
Klausur
Exam repetition information
Prerequisites and conditions Prerequisites Frequency Compulsory attendance Share on module grade in percent
Course 1 Summer semester No %
Course 2 Summer semester No %
Course 3 Summer semester No %
Course 4 Summer semester No %
Course 5 Summer semester No %