Basic knowledge of natural products (terpenes, fatty acids, proteins, carbohydrates and selected alkaloids)
- Basic knowledge of daily occurring products (fibers, dyes, tensides, selected drugs, renewable resources) - Knowledge on enzyme classes and mechanisms relevant for the selective synthesis of active compounds and chemicals - Basic knowledge on enzyme screening, characterization, and selectivity - Basic knowledge on enzyme and reaction engineering - Basic knowledge of methods in top-down systems biology (-omics methods, statistics) - Basic knowledge of methods in bottom-up systems biology (modeling and simulation of biological networks) - Basic knowledge of the principles and objectives of metabolic engineering - Basic knowledge of methods in metabolic engineering (gene identification, gene isolation, gene expression and its optimization)
Modulinhalte
Course B-InBT.1 Basics of organic chemistry of natural products
Data analysis and visualization (clustering, graphs, over-representation analysis)
Principles of mathematical modeling of biological networks
Course B-InBT.4 Basics of metabolic engineering
Why metabolic engineering? (Process optimization, production of chemicals using renewable resources, new chemicals, chemical sourcing)
Objects of metabolic engineering (biofuels, commodity chemicals/high value products) and associated constraints (regulatory, environmental, process, financial)
Methods in metabolic engineering: Gene identification and sourcing (literature and genome data mining, pathway discovery), different host types (microorganisms, algae, plants)
Engineering optimization based on metabolic modelling
Optimization based on improvement of gene expression (codon optimization, expression levels, protein stabilization, enzymatic properties)
Plant metabolic engineering: Potential, challenges and current progress
Lehrveranstaltungsformen
Seminar (8 SWS)
Kursus
Unterrichtsprachen
Deutsch, Englisch
Dauer in Semestern
1 Semester Semester
Angebotsrhythmus Modul
jedes Wintersemester
Aufnahmekapazität Modul
unbegrenzt
Prüfungsebene
Credit-Points
10 CP
Modulabschlussnote
LV1: %; LV2: %.
Faktor der Modulnote für die Endnote des Studiengangs